Chemistry PYQ 321 of 346 · Everyday Chemistry

Which of the following statements about erythromycin is incorrect?

  1. AIt is a macrocyclic compound
  2. BIt can be used as an antibiotic
  3. CIt has good coverage for legionellosis
  4. DIt cannot be produced by fermentation from a strain of *Saccharopolyspora erythraea*

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Correct answer: (d) It cannot be produced by fermentation from a strain of *Saccharopolyspora erythraea*

Explanation

Statement (d) is the incorrect one: erythromycin is produced by fermentation using the bacterium *Saccharopolyspora erythraea* (formerly *Streptomyces erythreus*).

The other statements are true:

  • it is a macrolide, with a large macrocyclic lactone ring;
  • it is an antibiotic, often used for people allergic to penicillin;
  • it works against *Legionella*, the cause of legionellosis (Legionnaires' disease).
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